Polypharmacy in the elderly from the clinical toxicologist perspective
| Autor: | W. Mühlberg, Katrin Singler, Cornel C. Sieber, Hans Jürgen Heppner, Michael Christ, Markus Gosch, Philipp Bahrmann, Thomas Bertsch |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Health (social science) Drug-Related Side Effects and Adverse Reactions health care facilities manpower and services Clinical toxicology Risk Assessment Risk Factors Germany Medicine Multimorbidity Humans Drug Interactions Intensive care medicine Aged Polypharmacy Aged 80 and over business.industry Geriatrics gerontology Incidence Poisoning fungi Perspective (graphical) food and beverages social sciences Survival Analysis humanities Survival Rate Issues ethics and legal aspects Female Geriatrics and Gerontology business Gerontology |
| Zdroj: | Zeitschrift fur Gerontologie und Geriatrie. 45(6) |
| ISSN: | 1435-1269 |
| Popis: | Polypharmacy is closely associated with multimorbidity in the elderly and can lead to problems and drug interactions.This study assessed polypharmacy in the elderly, tracking inquiries to the Poison Information Centre Nuremberg (PICN) and patients needing toxicological intensive care therapy.From 2006-2009, all PICN inquiries involving individuals 70 years were tracked, as were cases at the Toxicological Intensive Care Unit (T-ICU) regarding adverse drug reactions (ADRs) and drug poisoning.Of 11,683 PICN calls about pharmaceuticals, 175 (1.5%) were from people 70 years; 156 (4.8%) of 3,272 T-ICU patients were 70 years. Calls about psychopharmaceuticals (46.9%) and analgesics (25.7%) were most frequent. Among the T-ICU patients, psychopharmaceuticals like sedatives and hypnotics were frequently involved (20.5%), as were tricyclic antidepressants (17.9%) and analgesics (29.5%). Ethanol was co-ingested by 18.3%.Population-specific poison prevention strategies are needed to reduce toxic exposures. Such strategies could include pharmacist intervention, improved prescriber communication and education regarding the geriatric population, and computerized drug databases. |
| Databáze: | OpenAIRE |
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