Figure S1-S5, Table S1 from MEX3A Mediates p53 Degradation to Suppress Ferroptosis and Facilitate Ovarian Cancer Tumorigenesis

Autor: Wendy W. Hwang-Verslues, Li-Tzu Cheng, Yi-Jen Chen, Yen-Hou Chang, Chen-Hsin Albert Yu, Samyuktha Sridharan, Fang-Pei Chang, Grace Y.T. Tan, Tzu-Jou Chen, Cheng-Kai Wang
Rok vydání: 2023
Popis: Table S1. Short tandem repeat of ovarian teratocarcinoma and clear cell carcinoma cell line. Figure S1. MEX3A expression promoted tumorigenic ability and cell survival in WT p53 OC cells. Figure S2. The p53 pathway was enriched in upregulated genes in MEX3A-depleted OC cells expressing WT p53. Figure S3. Stabilized WT p53 protein in MEX3A-depleted cells was activated. MEX3A did not interact with or affect the level of mutant p53 protein. Figure S4. p53 depletion alone did not significantly affect cell proliferation or cell death in MEX3A expressing WT p53 OC cells. Figure S5. MEX3A and MDM2 in OC.
Databáze: OpenAIRE