Circulating Endothelial Cells in Renal Transplant Recipients
| Autor: | Patrick B. Mark, Alan G. Jardine, H L Elliott, A.S. Mohamed, Dianne Z. Hillyard, Jacqueline Thomson, Kenneth J. McDonald |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Population Disease Gastroenterology Age Distribution Reference Values Internal medicine medicine Humans In patient Endothelial dysfunction education Normal control Aged Transplantation education.field_of_study business.industry Endothelial Cells Middle Aged medicine.disease Kidney Transplantation Cardiovascular Diseases Allograft rejection Renal transplant cardiovascular system Female Surgery business |
| Zdroj: | Transplantation Proceedings. 37:2387-2390 |
| ISSN: | 0041-1345 |
| Popis: | Circulating endothelial cells (CECs) are a marker of endothelial injury and endothelial dysfunction. We measured CECs in 95 patients with functioning renal transplants at risk of premature cardiovascular (CV) disease and in normal control subjects. We were unable to demonstrate consistent relationships between CEC levels and conventional CV risk factors in transplant recipients. However, CEC levels were increased in patients with a history of rejection. We conclude that CECs are of little use as a marker of CV risk in this population but may be a useful marker to monitor allograft rejection. |
| Databáze: | OpenAIRE |
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