Hypolipidemic Activity of Eryngium carlinae on Streptozotocin-Induced Diabetic Rats
| Autor: | Omar Ortiz-Avila, Alfredo Saavedra-Molina, Istvan Boldogh, Rafael Salgado-Garciglia, Monica Clemente-Guerrero, Christian Cortés-Rojo, Ruth Noriega-Cisneros, Salvador Manzo-Avalos, Edgar Esquivel-Gutiérrez |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Creatinine Article Subject endocrine system diseases business.industry nutritional and metabolic diseases Streptozotocin medicine.disease Biochemistry lcsh:Biochemistry chemistry.chemical_compound Endocrinology chemistry Internal medicine Total cholesterol Diabetes mellitus Hyperlipidemia medicine Uric acid lcsh:QD415-436 Significant risk business Eryngium carlinae medicine.drug Research Article |
| Zdroj: | Biochemistry Research International Biochemistry Research International, Vol 2012 (2012) |
| ISSN: | 2090-2255 2090-2247 |
| Popis: | Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate the effect of chronic administration of ethanolic extract ofEryngium carlinaeon glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum of streptozotocin- (STZ-) induced diabetic rats. Triglycerides, total cholesterol, and uric acid levels increased in serum from diabetic rats. The treatment withE. carlinaeprevented these changes. The administration ofE. carlinaeextract reduced the levels of creatinine, uric acid, total cholesterol, and triglycerides. Thus administration ofE. carlinaeis able to reduce hyperlipidemia related to the cardiovascular risk in diabetes mellitus. |
| Databáze: | OpenAIRE |
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