Structural elucidation of two new megastigmane glycosides from the leaves of AquiAquilaria sinensi
| Autor: | Ke-Yuan Wang, Peng-Fei Tu, Fang Xia, Shu Wang, Jian Sun, Jin-Ming Chen |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Magnetic Resonance Spectroscopy
Stereochemistry Aquilaria sinensis Mass spectrometry chemistry.chemical_compound Column chromatography Cucurbitacins Glucosides Drug Discovery chemistry.chemical_classification biology Traditional medicine Cyclohexanones Chemistry Silica gel Glycoside General Medicine biology.organism_classification Plant Leaves Complementary and alternative medicine Thymelaeaceae Sephadex Bryoamaride Norisoprenoids Chromatography Liquid |
| Zdroj: | Chinese Journal of Natural Medicines. 13:290-294 |
| ISSN: | 1875-5364 |
| Popis: | The present study was designed to determine the chemical constituents and identify new components of the leaves of Aquilaria sinensis (Lour.) Gilg. The compounds were isolated and purified by repeated silica gel, Sephadex LH-20, and ODS column chromatography and their structures were elucidated by NMR and HR-ESI-MS spectrometry. Eight megastigmane glycosides and two cucurbitacins were isolated and identified as (9S) megastigma-4,7-diene-2,3,9-triol 9-O-β-D-glucopyranoside (1), (9S) megastigma-4(13),7-diene-3,6,9-triol 9-O-β-D-glucopyranoside (2), macarangloside D (3), corchoionoside C (4), staphylionoside H (5), (+) 3-oxo-α-ionol-β-D-glucopyranoside (6), (-) 3-oxo-α-ionol-β-D-glucopyranoside (7), citroside B (8), 2-O-β-D-glucopyranosyl cucurbitacin I (9), bryoamaride (10). Compounds 1 and 2 were newly identified megstigmane glucosides and reported from this genus for the first time. |
| Databáze: | OpenAIRE |
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