Impact of muscle mass on blood glucose level
| Autor: | Lenah Almusallam, Nafish Haider, Thekra Al Maqati, Gharam Altalib, Deema Alowfi, Murtada Taha, Yaser A Al-Naam |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
Blood Glucose Physiology Subgroup analysis Myostatin Muscle mass Body Mass Index Correlation Diabetes mellitus Drug Discovery Humans Medicine Muscle Skeletal Pharmacology biology business.industry Type 2 Diabetes Mellitus General Medicine medicine.disease Glucose Diabetes Mellitus Type 2 biology.protein business Bioelectrical impedance analysis Body mass index |
| Zdroj: | Journal of Basic and Clinical Physiology and Pharmacology. 33:779-787 |
| ISSN: | 2191-0286 |
| Popis: | Objectives At present, diabetes is one of the leading causes of mortality across the world. It was hypothesized that muscle mass could have a significant influence on blood glucose level and this corelation if established successfully could pave way for novel treatment modalities for type 2 diabetes mellitus (T2DM). In the present study, the association between muscle mass and blood glucose level was examined in a healthy population who was not having T2DM at baseline and was undergoing a regular course of exercise. Methods The clinical study was performed involving 53 healthy male populations between 10 and 60 years of age. The participants were sampled in accordance with the quantitative experimental study design, using nonprobability sampling techniques. The independent variable measured among the subjects included muscle mass and blood glucose level, using bioelectrical impedance and a simple glucometer respectively. Subgroup analysis amongst different substantial parameters including body mass index (BMI), myostatin inhibitor usage, and age factor that could affect the muscle mass and glucose level correlation were also studied simultaneously. Results The study findings demonstrated a negative correlation between muscle mass and glucose utilization levels. There was a significant difference in the mean muscle mass of the participants which was 36.2453, and the mean glucose utilization level which was 15.1493%. Pearson correlation between the muscle mass and percentage of glucose utilization of the participants indicated a significant difference (since p-value . Conclusions The study finding suggests an inverse association of the skeletal muscle mass with blood glucose level which encourages the implication of muscle-building exercises as the preventive measure for T2DM. |
| Databáze: | OpenAIRE |
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