Prediction of Extubation Readiness Using Transthoracic Ultrasound in Preterm Infants
| Autor: | Rania H. Hashem, Hany Aly, Reem N. Said, Abdulaziz M. Abdulbaqi, Yasser Elsayed, Reem M. Soliman |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Neonatal intensive care unit Receiver operating characteristic Respiratory distress business.industry Ultrasound Area under the curve Diastole medicine.anatomical_structure Anesthesia Internal medicine Ductus arteriosus medicine.artery Pulmonary artery medicine Cardiology Gestation Interventricular septum Systole Prospective cohort study business |
| DOI: | 10.1101/2020.04.26.20080739 |
| Popis: | ObjectiveTo test the hypothesis that a lung ultrasound severity score (LUSsc) and assessment of left ventricular eccentricity index of the interventricular septum (LVEI) by focused heart ultrasound can predict extubation success in mechanically ventilated preterm infants with respiratory distress syndrome (RDS).DesignProspective observational study of premature infants SettingLevel III neonatal intensive care unit, Cairo, Egypt.ResultsA total of 104 studies were performed to 66 infants; of them 39 had mild RDS (LUSsc 0–9) and 65 had moderate-severe RDS (score ≥10). LUSsc predicted extubation success with a sensitivity and a specificity of 91% and 69%; the positive and negative predictive values were 61% and 94%, respectively. Area under the curve (AUC) was 0.83 (CI: 0.75-0.91). LVEI did not differ between infants that succeeded and failed extubation. However, it correlated with pulmonary artery pressure during both systole (r=0.62) and diastole (r=0.53) and with hemodynamically significant patent ductus arteriosus (r=0.27 and r=0.46, respectively).ConclusionLUSsc predicts extubation success in preterm infants with RDS whereas LVEI correlates with high PAP. |
| Databáze: | OpenAIRE |
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