Specificity of Lower Urinary Tract Symptoms in Neuromyelitis Optica in Comparison With Multiple Sclerosis Patients
| Autor: | Samer Sheikh Ismael, Frédérique Le Breton, Camille Chesnel, A. Charlanes, Gérard Amarenco, Arnaud Declemy |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Urology Urinary system 030232 urology & nephrology lcsh:RC870-923 Multiple sclerosis 03 medical and health sciences 0302 clinical medicine Lower urinary tract symptoms Internal medicine medicine Nocturia Clinical Investigation Neuromyelitis optica Expanded Disability Status Scale Urinary retention business.industry Devic disease medicine.disease lcsh:Diseases of the genitourinary system. Urology Neurology Overactive bladder Voiding disorder Original Article Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | International Neurourology Journal, Vol 22, Iss 3, Pp 185-191 (2018) International Neurourology Journal |
| ISSN: | 2093-6931 2093-4777 |
| Popis: | Purpose The aim of this study was to describe lower urinary tract symptoms in neuromyelitis optica (NMO), and to compare these data with urinary disorders observed in multiple sclerosis (MS) patients. Methods Retrospective study of data collected from January 1997 to July 2017 using the database from a Neuro-Urology Department of a university hospital. NMO and MS patients were matched for sex, age, and Expanded Disability Status Scale (EDSS). Results Twenty-six patients with NMO were included and compared with 33 MS patients. Mean age was 41.6 years (standard deviation [SD], 14,8), mostly female patients (24 vs. 2 males). Mean EDSS was 4.6 (SD, 1.8) in the 2 groups. In NMO group, 57% of the patients (n=15) had overactive bladder with urgency and urge incontinence and 38.5% (n=10) of them had nocturia. Voiding symptoms was observed in 69.2% of the patients (n=18); 42.3% of NMO patients performed self-intermittent catheterization versus 12.1% in MS patients (P=0.012). Low bladder compliance and severe urinary tract infections (pyelonephritis) were more frequent in NMO than in MS patients (respectively 15% vs. 0%, P=0.016 and 42% vs. 12%, P=0.024). Conclusion Lower urinary tract symptoms, especially overactive bladder and urinary retention, are frequent in NMO. Low bladder compliance, serious urinary infections, and high prevalence of urinary retention requiring self-intermittent catheterization are the main symptoms significantly more frequent than in MS. |
| Databáze: | OpenAIRE |
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