A chemoselective oxidation of monosubstituted ethylene glycol: Facile synthesis of optically active ?-hydroxy acids
| Autor: | Kiran Chinthapally, Sundarababu Baskaran |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Ethylene Glycol
Chemistry Organic Chemistry Chemistry Organic Temperature Carbohydrate Optically active Buffers Biochemistry Catalysis Solvent Cyclic N-Oxides chemistry.chemical_compound Reaction temperature Acetals Reagent Solvents Organic chemistry Physical and Theoretical Chemistry Carboxylic acids Ethylene glycol Functional groups Polyols Chemoselective oxidation Facile synthesis Hydroxy acids Optically Active Reagent systems Oxidation acetal derivative amine oxide buffer ethylene glycol hydroxyacid solvent TEMPO catalysis chemistry organic chemistry oxidation reduction reaction procedures synthesis temperature Hydroxy Acids Oxidation-Reduction |
| Zdroj: | IndraStra Global. |
| ISSN: | 2381-3652 |
| Popis: | A mild and efficient method for the synthesis of optically active ?-hydroxy acids through chemoselective oxidation of monosubstituted ethylene glycols using the TEMPO-NaOCl reagent system is described. It is evident from our studies that the solvent, pH and reaction temperature are very crucial for the success of this oxidation. The versatility of this method has been demonstrated with a variety of aliphatic, aromatic and carbohydrate substrates bearing various functional groups. � the Partner Organisations 2014. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|