Resolution of recurrent aphthous ulcers after discontinuation of cow’s milk protein intake
| Autor: | Anuradha Nayudu, Nita Chainani-Wu |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Gastroenterology Elevated blood 03 medical and health sciences 0302 clinical medicine Recurrence Internal medicine medicine Animals Humans Ingestion In patient 030212 general & internal medicine Oral ulcers Child General Dentistry Practical implications business.industry Circulating antibodies 030206 dentistry Milk Proteins Discontinuation Surgery carbohydrates (lipids) Cow's milk protein Cattle Female Stomatitis Aphthous business Food Hypersensitivity |
| Zdroj: | The Journal of the American Dental Association. 148:614-617 |
| ISSN: | 0002-8177 |
| DOI: | 10.1016/j.adaj.2017.02.028 |
| Popis: | Background and Overview Authors of published studies have reported elevated levels of circulating antibodies to cow's milk protein (CMP) in patients with recurrent aphthous ulcers (RAUs), and authors of case reports have described resolution of RAU after dairy elimination. Case Description A 10-year-old girl and an 11-year-old boy, both with 5-year histories of frequent RAU episodes, with multiple ulcerations, underwent dairy elimination trials. Both were free of oral ulcers within 2 weeks of discontinuing CMP and remained so with a CMP-free diet. In addition, the first patient had recurrence of ulcerations after occasional ingestion of CMP-containing foods. She showed elevated blood levels of immunoglobulin E in reaction to CMP and soy. Soy intake did not trigger the ulcerations. Conclusions and Practical Implications The proportion of patients with RAU in whom CMP acts as a trigger is unknown. However, CMP elimination trials are safe and feasible and, therefore, should be considered, particularly before use of medications with potential side effects. |
| Databáze: | OpenAIRE |
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