Mutagenicity of HPLC fractions from extracts of AAtrex-treated corn
| Autor: | I. Singh, Peter M. McGuire, A. F. Lusby |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Chromatography
Strain (chemistry) Plant Extracts Health Toxicology and Mutagenesis Saccharomyces cerevisiae Gene Conversion Mutagen Fraction (chemistry) DNA Biology medicine.disease_cause biology.organism_classification High-performance liquid chromatography Zea mays chemistry.chemical_compound chemistry Genes Genetics medicine RNA Atrazine Methanol Chromatography High Pressure Liquid Mutagens |
| Zdroj: | Environmental mutagenesis. 4(1) |
| ISSN: | 0192-2521 |
| Popis: | Crude extracts from maize plants treated with varying concentrations of AAtrex, an s-triazine herbicide, were tested for the induction of gene conversion in a diploid strain of Saccharomyces cerevisiae heteroallelic at two loci. These extracts were then subjected to analysis by higher pressure liquid chromatography (HPLC), and the fractions collected in water, 50% methanol, and 100% methanol were similarly tested. Dose-dependent convertogenic activity observed in the 50% methanol fractions suggested that the mutagen(s) is recovered in this fraction. |
| Databáze: | OpenAIRE |
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