Plasma apelin levels in patients with polycystic ovary syndrome
Autor: | Noyan, Aykan Yucel, Nevin Sagsoz, Gören K, Mehmet Sühha Bostancı, Osman Caglayan |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: |
medicine.medical_specialty
endocrine system diseases lcsh:Medicine waist to hip ratio lcsh:Gynecology and obstetrics Ferriman Gallwey score (FGS) chemistry.chemical_compound Waist–hip ratio Insulin resistance Internal medicine medicine Homeostatic Model Assessment insulin resistance (HOMA-IR) lcsh:RG1-991 Original Investigation Cholesterol business.industry lcsh:R Obstetrics and Gynecology nutritional and metabolic diseases medicine.disease Polycystic ovary female genital diseases and pregnancy complications Apelin Endocrinology chemistry polycystic ovary syndrome Ovarian cancer business Homeostasis Hormone |
Zdroj: | Journal of the Turkish-German Gynecological Association, Vol 13, Iss 01, Pp 27-31 (2012) |
Popis: | The aim of the study was to evaluate plasma apelin levels in patients with polycystic ovary syndrome (PCOS) and healthy controls.Plasma apelin levels, serum lipid levels, serum hormone levels, and homeostasis model assessment-insulin resistance (HOMA-IR) values of 32 patients with PCOS and 31 healthy women forming the control group were checked.Plasma apelin levels of the PCOS group (0.350±0.083 ng/ml) were significantly higher than those of the control group (0.246±0.045 ng/ml) (p0.001). No significant correlation was detected between apelin levels and biochemical or clinical data in PCOS group.Plasma apelin levels were significantly higher in PCOS patients.Bu çalışmanın amacı, polikistik over sendromu (PKOS) hastaları ve sağlıklı kontrol grubundaki hastalarda, plazma apelin düzeylerini değerlendirmektir.Plazma apelin düzeyleri, serum lipid düzeyleri, serum hormon düzeyleri ve homeostasis model assessment-insulin rezistans (HOMA-IR) değerleri 32 PCOS’lu hasta ve sağlıklı kadın kontrol grubunu oluşturan 31 hastada ölçüldü.Plazma apelin düzeyleri PKOS grubunda (0.350±0.083 ng/ml), kontrol grubuna göre (0.246±0.045 ng/ml) (p0.001) anlamlı olarak daha yüksek bulundu. PKOS grubundaki apelin düzeyleri ile biyokimyasal veya klinik veriler arasında anlamlı bir ilişki tespit edilmedi.Plazma apelin düzeyleri PCOS’lu hastalarda anlamlı olarak daha yüksektir. |
Databáze: | OpenAIRE |
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