Improvement in Skeletal Muscle Strength and Plasma Levels of Follistatin and Myostatin Induced by an 8-Week Resistance Training and Epicatechin Supplementation in Sarcopenic Older Adults
| Autor: | Soheil Biglari, Farnoosh Mafi, Alireza Ghardashi Afousi, Abbas Ali Gaeini |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Follistatin Sarcopenia endocrine system medicine.medical_specialty Physical Therapy Sports Therapy and Rehabilitation Myostatin Catechin 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Muscle Strength 030212 general & internal medicine Muscle Skeletal Aged biology business.industry Rehabilitation Resistance training Skeletal muscle Resistance Training 030229 sport sciences Plasma levels musculoskeletal system medicine.disease TGF-beta Superfamily Proteins body regions Treatment Outcome Endocrinology medicine.anatomical_structure Dietary Supplements biology.protein Muscle strength Female Geriatrics and Gerontology business human activities Gerontology Biomarkers hormones hormone substitutes and hormone antagonists |
| Zdroj: | Journal of Aging and Physical Activity. 27:384-391 |
| ISSN: | 1543-267X 1063-8652 |
| DOI: | 10.1123/japa.2017-0389 |
| Popis: | To investigate the effects of resistance training and epicatechin supplementation on muscle strength, follistatin, and myostatin in older adults with sarcopenia, a total of 62 males with sarcopenia (68.63 ± 2.86 years) underwent a supervised 8-week randomized controlled trial. Participants were divided into resistance training (RT), epicatechin (EP), resistance training+epicatechin (RT+EP), and placebo (PL) in a double-blind method. A pretest and posttest measurement was conducted. One-way analysis of variance was used to analyze between-group differences. The significantly greatest increase was observed in follistatin, follistatin/myostatin ratio, leg press, and chest press in RT+EP comparing RT, EP, and PL groups, whereas myostatin decreased significantly only in RT+EP and RT groups. However, appendicular muscle mass index and timed up and go test were enhanced significantly in all experimental groups than the PL group ( |
| Databáze: | OpenAIRE |
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