Cardiac Surgery is Safe in Female Patients with a History of Breast Cancer

Autor: Marcus Leistner, Ivan Aleksic, Elisa Schmidt-Hengst, Stefanie Sommer, Rainer Leyh, Christoph Schimmer, Sebastian-Patrick Sommer
Rok vydání: 2016
Předmět:
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Time Factors
Heart Valve Diseases
Breast Neoplasms
Coronary Artery Disease
Kaplan-Meier Estimate
030204 cardiovascular system & hematology
Hematocrit
Risk Assessment
Coronary artery disease
03 medical and health sciences
0302 clinical medicine
Breast cancer
Risk Factors
Humans
Medicine
Coronary Artery Bypass
Aged
Proportional Hazards Models
Retrospective Studies
Heart Valve Prosthesis Implantation
medicine.diagnostic_test
business.industry
Patient Selection
Incidence (epidemiology)
Gastroenterology
Retrospective cohort study
General Medicine
Perioperative
Middle Aged
medicine.disease
Surgery
Cardiac surgery
Treatment Outcome
030220 oncology & carcinogenesis
Concomitant
Female
Original Article
Cardiology and Cardiovascular Medicine
business
Zdroj: Annals of Thoracic and Cardiovascular Surgery. 22:168-173
ISSN: 2186-1005
1341-1098
Popis: Purpose: In cardiac surgery candidates, a concomitant history of breast cancer suggests adverse outcomes. The possibility of internal mammary artery (IMA) utilization and its patency rate is frequently discussed. Secondary, blood loss and wound related infections might be important issues. However, publications focusing on these issues are limited. Methods: We analyzed 32 patients with previously treated breast cancer undergoing cardiac bypass (CABG) and combined CABG surgery matched to 99 control subjects in a retrospective cohort study. Patients were analyzed regarding IMA utilization, blood loss and substitution and frequent perioperative complications as well as long-term mortality. Results: No significant differences between groups were observed regarding duration of surgery, IMA-utilization, incidence of infections and postoperative complications or mortality. A pronounced decline of hemoglobin/hematocrit was evident within the first 6 postoperative hours (3.3 ± 1.8 vs. 2.5 ± 1.8 mg/dl; p = 0.03) in breast cancer patients not related to an increased drainage loss but associated with an increase of international normalized ratio (INR) (0.39 ± 0.16 vs. 0.29 ± 0.24; p
Databáze: OpenAIRE
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