Dietary habits during the 2 months following the Chernobyl accident and differentiated thyroid cancer risk in a population-based case–control study
| Autor: | Martin Schlumberger, Yan Ren, Françoise Borson-Chazot, J. Orgiazzi, Constance Xhaard, Laurent Bailly, Emilie Marrer, Michel Velten, Anne Sophie Woronoff, Carole Rubino, Geneviève Sassolas, Stephane Maillard, Vladimir Drozdovitch, Claire Schvartz, Florent de Vathaire, André Bouville, Brigitte Lacour, Eugènia Mariné Barjoan, Vincent Souchard, Elisabeth Adjadj, Marc Colonna |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Radioactive Fallout Cancer Research Neoplasms Radiation-Induced Adolescent Epidemiology Population based Article 03 medical and health sciences Young Adult 0302 clinical medicine Risk Factors Environmental health Adenocarcinoma Follicular medicine Humans 030212 general & internal medicine Thyroid Neoplasms Child Thyroid cancer Food Contamination Radioactive Potential impact business.industry Thyroid Case-control study Infant Newborn Infant Odds ratio Feeding Behavior medicine.disease Carcinoma Papillary Diet medicine.anatomical_structure Oncology Chernobyl Nuclear Accident 030220 oncology & carcinogenesis Case-Control Studies Child Preschool Female Leafy vegetables France business Contaminated food |
| Zdroj: | Cancer Epidemiol |
| Popis: | Background The Chernobyl nuclear power plant accident occurred in Ukraine on April 26th 1986. In France, the radioactive fallout and thyroid radiation doses were much lower than in highly contaminated areas. However, a number of risk projections have suggested that a small excess in differentiated thyroid cancer (DTC) might occur in eastern France due to this low-level fallout. In order to investigate this potential impact, a case–control study on DTC risk factors was started in 2005, focusing on cases who were less than 15 years old at the time of the Chernobyl accident. Here, we aim to evaluate the relationship between some specific reports of potentially contaminated food between April and June 1986 – in particular fresh dairy products and leafy vegetables – and DTC risk. Methods After excluding subjects who were not born before the Chernobyl accident, the study included 747 cases of DTC matched with 815 controls. Odds ratios were calculated using conditional logistic regression models and were reported for all participants, for women only, for papillary cancer only, and excluding microcarcinomas. Results The DTC risk was slightly higher for participants who had consumed locally produced leafy vegetables. However, this association was not stronger in the more contaminated areas than in the others. Conversely, the reported consumption of fresh dairy products was not statistically associated with DTC risk. Conclusion Because the increase in DTC risk associated with a higher consumption of locally produced vegetables was not more important in the most contaminated areas, our study lacked power to provide evidence for a strong association between consumption of potentially contaminated food and DTC risk. |
| Databáze: | OpenAIRE |
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