Synthesis and reactivity of enantiomerically pure N-acylN-alkyl p-toluenesulfinamides

Autor:	Pedro Noheda Marín, Maria M. Zarzuelo, Raquel Alonso, José L. García-Ruano
Přispěvatelé:	Dirección General de Investigación Científica y Técnica, DGICT (España)
Jazyk:	angličtina
Rok vydání:	1995
Předmět:	Inorganic Chemistry chemistry.chemical_classification chemistry Organic Chemistry Reactivity (chemistry) lipids (amino acids peptides and proteins) Physical and Theoretical Chemistry Medicinal chemistry Catalysis Alkyl
Zdroj:	Digital.CSIC. Repositorio Institucional del CSIC instname
Popis:	The syntheses of different enantiomerically N-acyl N-alkyl p-toluenesulfinamides 5, by N-sulfinylation of primary amines with (S)-menthyl-p-tolylsulfinate followed by N-acylation of the resulting sulfinamides are reported. Their reactions with some C-nucleophiles take place at the sulfur atom exclusively with complete retention of the enantiomeric purity, revealing their ability as sulfinylating agents. In this sense, their comparison with other reagents popularly used, revealed that 5 have some important advantages. We gratefully acknowledge DGICYT for financial support (Grant PB-92-0162 and PB93-257)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eafc80bad8cf86789f36c7acba6ccec http://hdl.handle.net/10261/217455 Zobrazit plný text záznamu