Nodular lymphoid hyperplasia in common variable immunodeficiency
| Autor: | Antonio Gil-Aguado, Ismael Said-Criado |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Diarrhea Male medicine.medical_specialty Lymphoid Tissue Tonsillitis Disease Gastroenterology Lymphoid hyperplasia Ileum Internal medicine medicine Humans Gastrointestinal Transit music Hyperplasia music.instrument business.industry Common variable immunodeficiency digestive oral and skin physiology General Medicine medicine.disease Follicular hyperplasia Common Variable Immunodeficiency Nodular lymphoid hyperplasia Intraepithelial lymphocyte Bronchitis medicine.symptom business |
| Zdroj: | The Lancet. 383:e2 |
| ISSN: | 0140-6736 |
| Popis: | A 32-year-old man with a history of recurrent sinusitis, bronchitis, and tonsillitis since 12 years of age came to our clinic. He reported diarrhoea of more than 2 weeks’ duration. The patient had been diagnosed with common variable immunodefi ciency (CVID) 6 years before and had been treated since with monthly immunoglobins. Because of the patient’s recent history of diarrhoea, gastrointestinal transit, ileoscopy, and ileal biopsy were done. The gastrointestinal transit (fi gure) showed accelerated transit and several nodular repletion defects in terminal ileum, compatible with nodular follicular hyperplasia. Ileoscopy confi rmed lymphoid hyperplasia. Among enteropathies associated with CVID, moderate increase in intestinal intraepithelial lymphocytes occurring in CVID can be the cause of chronic diarrhoea in these patients. Diff erential diagnoses include lymphoproliferative diseases and infl ammatory bowel disease. |
| Databáze: | OpenAIRE |
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