In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark
| Autor: | Vinay J Shukla, Mukesh B Nariya, Nayan R Bhalodia, Pankaj B Nariya, Rabinarayan Acharya |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Antioxidant
anti–radical DPPH medicine.medical_treatment chemistry.chemical_compound Pharmacological Study medicine reducing power Organic chemistry Gallic acid biology Traditional medicine Butanol Cordia dichotoma Shleshmataka General Medicine biology.organism_classification Ascorbic acid diphenyl–2 In vitro picrylhydrazyl chemistry visual_art visual_art.visual_art_medium Bark |
| Zdroj: | Ayu |
| ISSN: | 0974-8520 |
| Popis: | Cordia dichotoma Forst. f. bark, identified as botanical source of Shleshmataka in Ayurvedic pharmacopoeia. Present investigation was undertaken to evaluate possible antioxidant potential of methanolic and butanol extract of C. dichotoma bark. In vitro antioxidant activity of methanolic and butanol extract was determined by 1,1, diphenyl-2, picrylhydrazyl (DPPH) free radical scavenging assay. The extracts were also evaluated for their phenolic contents and antioxidant activity. Phenolic content was measured using Folin-Ciocalteu reagent and was calculated as Gallic acid equivalents. Antiradical activity of methanolic extract was measured by DPPH assay and was compared to ascorbic acid and ferric reducing power of the extract was evaluated by Oyaizu method. In the present study three in vitro models were used to evaluate antioxidant activity. The first two methods were for direct measurement of radical scavenging activity and remaining one method evaluated the reducing power. The present study revealed that the C. dichotoma bark has significant radical scavenging activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|