Autor: |
Shizhen Emily Wang, Yukio Kuroki, Peggy Scherle, Hui Li, Xiubao Ren, Yuan-Zhong Wang, Yang Yu, Weiying Zhou, Shiuan Chen, Wei Ye, Xiwei Wu, Arthur Xuejun Li, Thehang Luu, Sofia Loera, Peiguo Chu, George Somlo, Jun Wu, Amy Chow, Akihiro Tsuyada |
Rok vydání: |
2023 |
Popis: |
PDF file - 111K, Methods: Includes Mammosphere formation assay, Cell transfection and reporter assays, RNAi studies, as well as Western blot analyses and xenograft data. Figures S1-S9 include the following: Marker expression in primary fibroblasts and BC cells (S1); Serial confocal images of representative mammospheres formed by PKH67-labeled BT474 cells in the presence or absence of CCL2 (S2); CCL2 expression in CAF3 cells upon CM treatments (S3); Sustained CCL2 induction in CAFs co-cultured with tumor cells (S4); Expression of CCR2 and CCR4 in BC cells (S5); HES1 and HEY1 reporter assays in BT474 cells (S6); In vitro secretase cleavage assay (S7); Representative IHC images of XP/CAF265922 xenograft tumors treated with PBS, IgG, or anti-CCL2 (S8); Representative IHC images of CCL2 and NOTCH1 in primary BC specimens (S9). |
Databáze: |
OpenAIRE |
Externí odkaz: |
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