Placental biopsy by frozen section: does it have a role in evaluation of fetal well-being?
| Autor: | Bahar Kilicarslan, Cahit Gürkan Zorlu, Bilal Trak, Mine Üner, Seyda Karaveli, Inanc Mendilcioglu |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Biopsy Placenta Placental biopsy Sensitivity and Specificity Fibrin Predictive Value of Tests Pregnancy Prenatal Diagnosis Chronic Villitis Medicine Frozen Sections Humans Permanent Section Retrospective Studies Fetus Frozen section procedure biology business.industry Postpartum Period Obstetrics and Gynecology General Medicine medicine.disease Pregnancy Complications medicine.anatomical_structure biology.protein Female business |
| Zdroj: | The AustralianNew Zealand journal of obstetricsgynaecology. 43(6) |
| ISSN: | 0004-8666 |
| Popis: | Aim: To assess the effectiveness of post-partum placental biopsy and frozen section evaluation in diagnosing pregnancy disorders. Study design: Between January and July 1998, biopsies were carried out on 100 newly delivered placentas. Biopsies were carried out using a 14-gauge needle, and frozen section evaluations were reviewed. These were compared to the standard evaluation of histological evaluation of the whole placenta sections. Specimens were evaluated by standard placental pathologic criteria. Results: Villous oedema which is associated with antenatal hypoxia was observed with a sensitivity of 78%, and specificity of 97%, yielding a positive predictive value of 84% in frozen section compared to standard placental evaluation. No statistical difference was observed in the evaluation of dysmaturity, intravillous fibrin agglutination and chronic villitis between frozen sectioning and whole placenta sections. Increased syncytial knots were detected with a sensitivity of 45% and specificity of 98%. Conclusion: Placental biopsy by frozen sectioning might be a useful and quick method of evaluation for placental pathology. Theoretically, fetal status could be more precisely evaluated by combining prenatal placental biopsy by permanent section with conservative ante-partum well-being tests. |
| Databáze: | OpenAIRE |
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