US Evaluation of Axillary Lymphadenopathy Following COVID-19 Vaccination: A Prospective Longitudinal Study

Autor:	Su Min Ha, A Jung Chu, JungBok Lee, Soo-Yeon Kim, Su Hyun Lee, Heera Yoen, Nariya Cho, Woo Kyung Moon, Jung Min Chang
Rok vydání:	2022
Předmět:	Adult Vaccines Synthetic COVID-19 Vaccines Vaccination COVID-19 Lymphadenopathy ChAdOx1 nCoV-19 Humans Female Radiology Nuclear Medicine and imaging Longitudinal Studies Prospective Studies RNA Messenger mRNA Vaccines BNT162 Vaccine 2019-nCoV Vaccine mRNA-1273
Zdroj:	Radiology. 305:46-53
ISSN:	1527-1315 0033-8419
DOI:	10.1148/radiol.220543
Popis:	Background Both temporal changes in imaging characteristics of lymphadenopathy on US scans after COVID-19 vaccination and expected duration of radiologically evident lymphadenopathy remain uncertain. Purpose To longitudinally evaluate COVID-19 vaccine-associated lymphadenopathy on axillary US scans at various time intervals in both messenger (mRNA) and vector vaccine recipients. Materials and Methods This prospective cohort study was conducted between March 2021 and January 2022. The participants were asymptomatic women without breast cancer who had received COVID-19 vaccination. Serial follow-up US was performed in women with lymphadenopathy. The following variables were assessed: cortical thickness, number of lymph nodes, morphologic characteristics, and Doppler signal. Temporal changes in cortical thickness and number of lymph nodes during follow-up were assessed using a linear mixed model. Results Ninety-one women with lymphadenopathy in the vaccinated arm had undergone a total of 215 serial US examinations (mean age, 44 years ± 13 [SD]). Fifty-one participants had received a vector vaccine (ChAdOx1 nCoV-19 vaccine) and 40 had received an mRNA vaccine (BNT162b2 vaccine [
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e98412eddb8322b4f966039717ab782 https://doi.org/10.1148/radiol.220543 Zobrazit plný text záznamu