Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India
| Autor: | Sonal Saxena, Rohit Chawla, Ritika Bakshi, S. Singh, Meera Dhuria, Saurav Basu, P. K. Bharti, Panna Lal, Pragya Sharma |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Population Psychological intervention communicable diseases Infectious and parasitic diseases RC109-216 01 natural sciences Occupational safety and health Immunoglobulin G 03 medical and health sciences 0302 clinical medicine Internal medicine Statistical significance Health care medicine Seroprevalence 030212 general & internal medicine 0101 mathematics education education.field_of_study biology business.industry 010102 general mathematics Public Health Environmental and Occupational Health virus diseases RC952-1245 Infectious Diseases covid-19 Special situations and conditions occupational health biology.protein Original Article Antibody business |
| Zdroj: | Osong Public Health and Research Perspectives, Vol 12, Iss 2, Pp 88-95 (2021) Osong Public Health and Research Perspectives |
| ISSN: | 2210-9110 2210-9099 |
| Popis: | Objective: Healthcare workers (HCWs) are at a high risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) due to the increased likelihood of clinical exposure during patient management. The study objective was to determine the seroprevalence of antibodies to SARS-CoV-2 and its predictors among hospital employees. Methods: The cross-sectional study was conducted at a teaching hospital from August 2020 to September 2020 among 1,401 employees, including 1,217 HCWs, in New Delhi, India. The serum samples were examined for immunoglobulin G (IgG) antibodies to SARS-CoV-2 using the COVID Kavach-Anti-SARS-CoV-2 IgG Antibody Detection enzyme-linked immunosorbent assay kit. Data were collected electronically using the EpiCollect mobile platform. A p < 0.05 was considered to indicate statistical significance. Results: A total of 169 participants (12.1%) had detectable IgG antibodies to SARS-CoV-2. The highest seropositivity rate was observed in the administrative staff (20.1%), while it was lowest among medical doctors (5.5%, p < 0.001). Male sex and ever having lived in a containment zone were independently associated with past infection with SARS-CoV-2. Conclusion: The seroprevalence of SARS-CoV-2 infection in health workers may be lower than in the general population in New Delhi. However, nonpharmaceutical interventions were not associated with a reduction in the risk of acquisition of SARS-CoV-2. |
| Databáze: | OpenAIRE |
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