Cefotaxime/sulbactam: clinical and pharmacological characteristics

Autor: A.V. Golub, E.A. Ortenberg
Jazyk: ruština
Rok vydání: 2019
Předmět:
Zdroj: Клиническая микробиология и антимикробная химиотерапия, Vol 21, Iss 3, Pp 212-216 (2019)
ISSN: 2686-9586
1684-4386
Popis: The recently approved cefotaxime/sulbactam, combination of third-generation cephalosporin (cefotaxime) and beta-lactamase inhibitor (sulbactam), can combat resistance mechanisms associated with the production of serine beta-lactamases, including some extended spectrum beta-lactamases. This paper reviews the use of this combination antibiotic in clinical practice based on the current data on antimicrobial resistance in pathogens causing lower respiratory tract infections and the results of completed clinical studies of its efficacy and safety.
Databáze: OpenAIRE