Two New Steroidal Saponins from Ypsilandra thibetica

Autor: Zhenhua Liu, Yong-Ai Si, Hai-Yang Liu, Ting-Xiang Lu, Wei Ni, Chang-Xiang Cheng, Huan Yan
Rok vydání: 2014
Předmět:
Zdroj: Natural Products and Bioprospecting
ISSN: 2192-2195
Popis: Two new monosaccharide steroidal saponins, named ypsilandroside S (1) and ypsilandroside T (2), have been isolated from the whole plants of Ypsilandra thibetica. Their structures were elucidated as heloniogenin 3-O-β-D-apiofuranoside (1) and pregna 5,16-dien-3β,12α-diol-20-one-3-O-β-D-apiofuranoside (2) by spectroscopic techniques (1D and 2D NMR, MS). Compounds 1 and 2 were tested for their inhibitory effects on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells. Graphical Abstract
Databáze: OpenAIRE