The nature of excessive sleepiness and sudden sleep onset in Parkinson׳s disease
| Autor: | Pedro Felipe Carvalhedo de Bruin, Iago Farias Jorge, Emily Mourão Soares Lopes, Rômulo Lopes Gama, Daniel Gurgel Fernandes Távora, Veralice Meireles Sales de Bruin |
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| Rok vydání: | 2014 |
| Předmět: |
Gerontology
Pediatrics medicine.medical_specialty Sleepiness Parkinson's disease genetic structures Injury control lcsh:BF1-990 genetic processes Neuroscience (miscellaneous) Medicine (miscellaneous) Excessive daytime sleepiness Poison control lcsh:Consciousness. Cognition Disease Article Behavioral Neuroscience Injury prevention medicine Sudden sleep onset Excessive sleepiness business.industry Diabetes biochemical phenomena metabolism and nutrition lcsh:BF309-499 medicine.disease Sleep attacks enzymes and coenzymes (carbohydrates) lcsh:Psychology Parkinson’s disease bacteria Sleep onset medicine.symptom business |
| Zdroj: | Sleep Science, Vol 7, Iss 1, Pp 13-18 (2014) Sleep Science |
| ISSN: | 1984-0063 |
| DOI: | 10.1016/j.slsci.2014.07.020 |
| Popis: | Objectives: Excessive daytime sleepiness (EDS) and sudden sleep onset (SOS) episodes are frequent in Parkinson׳s disease (PD). The objectives are to identify clinical characteristics and factors associated with EDS and SOS episodes. Methods: Clinical demographic data were recorded (N=100, mean age=65.0±10.4). EDS was identified by the Epworth Sleepiness Scale (ESS>10) and SOS episodes were registered. Disease severity was evaluated by the Unified Parkinson׳s Disease Rating Scale (UPDRS, I, II, and III), sleep disturbances by the Parkinson׳s Disease Sleep Scale (PDSS10) and rapid eye movement (REM) sleep behavior disorder (RBD) by the REM sleep behavior scale. Levodopa equivalent dose was measured. Results: PD patients with EDS (67%) were predominately male (73.1%) and had worse disease severity (UPDRS II and III p= 0.005); SOS episodes (39%) were associated with disease duration, diabetes, sleep disturbances (PDSS Scale), disease severity (UPDRS I, II, III) and RBD symptoms (p |
| Databáze: | OpenAIRE |
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