In vivo penetration of antibiotics into sputum in cystic fibrosis
Autor: | D. Lawson, B. A. Saggers |
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Jazyk: | angličtina |
Rok vydání: | 1968 |
Předmět: |
Cystic Fibrosis
medicine.drug_class Antibiotics Erythromycin Cystic fibrosis Methicillin Ampicillin medicine Humans Aerosols Infection Control Sulfonamides Lung Respiratory tract infections business.industry Sputum medicine.disease Acetylcysteine Anti-Bacterial Agents Lincomycin Molecular Weight medicine.anatomical_structure Pediatrics Perinatology and Child Health Immunology Cephaloridine Gentamicin Biological Assay medicine.symptom Gentamicins business Cloxacillin Novobiocin medicine.drug Research Article |
Popis: | The control of respiratory tract infections in cystic fibrosis has for many years utilized a wide range of antibiotics. The effect of administering one or more antibiotics to combat an invading organism has, as might be expected, been variable. We have attempted here to determine some of the factors that are responsible for these variations in the hope that a more effective chemotherapeutic control might result. The cases studied in this series were limited to those with extensive lung damage, as only in these cases could enough sputum be obtained for assay purposes. The results we have obtained, therefore, do not indicate the value of the test antibiotic in prophylaxis. |
Databáze: | OpenAIRE |
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