Soluble selectins and highly fucosylated ?1-antichymotrypsin in rheumatoid arthritis patients
| Autor: | Izabela Korczowska‑Łącka, Anna Olewicz‑Gawlik, Paweł Hrycaj |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
rheumatoid arthritis
medicine.medical_specialty selectins biology business.industry Acute-phase protein medicine.disease Leukocyte extravasation Endocrinology Internal medicine Rheumatoid arthritis acute phase proteins fucosylation biology.protein Medicine Rheumatoid factor α1 antichymotrypsin Antibody business Fucosylation Selectin |
| Zdroj: | Journal of Medical Science, Vol 84, Iss 1 (2015) |
| ISSN: | 2353-9801 2353-9798 |
| DOI: | 10.20883/medical.e33 |
| Popis: | Introduction. Fucosylation of acute phase proteins and serum soluble selectin levels is increased in rheumatoid arthritis (RA) patients and can influence leukocyte extravasation. Aim. The aim of this study was to evaluate the concentration and fucosylation of ?1-antichymotrypsin (ACT) in relation to serum concentrations of soluble forms of selectins in RA patients. Material and methods. Serum samples of 70 RA patients and 30 healthy controls were examined using sandwich enzyme-linked immunosorbent assay (ELISA). Results. ACT-FR was significantly increased in RA patients when compared to healthy controls (p |
| Databáze: | OpenAIRE |
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