COVID-19 Outbreak and Presymptomatic Transmission in Pilgrim Travelers Who Returned to Korea from Israel
| Autor: | Kwan Lee, Seok ju Yoo, Joon Ho Jang, Hyojung Shin, Ji-Hyuk Park |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Pilgrim Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Real-Time Polymerase Chain Reaction Asymptomatic Polymerase Chain Reaction Disease Outbreaks 03 medical and health sciences 0302 clinical medicine Epidemiology Republic of Korea medicine Transmission Humans 030212 general & internal medicine Israel Asymptomatic Infections Aged Travel Transmission (medicine) business.industry Medical record Outbreaks Outbreak COVID-19 General Medicine Infectious Diseases Microbiology & Parasitology Severe Acute Respiratory Syndrome Coronavirus 2 Middle Aged COVID-19 Nucleic Acid Testing Communicable Disease Control Original Article Female medicine.symptom business |
| Zdroj: | Journal of Korean Medical Science |
| ISSN: | 1598-6357 1011-8934 |
| Popis: | Background On February 21, 2020, 2 coronavirus disease 2019 (COVID-19) cases in pilgrim travelers from Korea to Israel were identified. We investigated the source of infection, clinical features of COVID-19, and transmission potential of presymptomatic and asymptomatic cases. Methods All 39 pilgrim travelers were aggressively tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their clinical features and possible source of infection were investigated by interview and review of their medical records. Ten confirmed cases without symptoms at the first sampling dates were selected for follow-up reverse transcription polymerase chain reaction tests. Results Of 39 pilgrim travelers, 30 (77%) were positive for SARS-CoV-2. Among the 30 positive COVID-19 cases, 4 (13%) were asymptomatic. Available follow-up cycle threshold values from 10 cases gradually increased over time and were lower during the presymptomatic period than during the postsymptomatic period. Out of 328 contacts related to the COVID-19 cases in the pilgrim travelers, 22 additional cases (7%) were confirmed with SARS-CoV-2 infections. Three tertiary cases were identified to be transmitted by presymptomatic secondary cases. Conclusion To prevent transmission of COVID-19, we need to focus on presymptomatic and asymptomatic cases, and massive testing for SARS-CoV-2 is required. More research about the possibility of presymptomatic transmission over 2 days before symptom onset is required. Graphical Abstract |
| Databáze: | OpenAIRE |
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