Langerhans Cells: the 'Yin and Yang' of HIV Restriction and Transmission
| Autor: | Bin Su, Luzia M. Mayr, Christiane Moog |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Langerin HIV Infections Microbiology 03 medical and health sciences 0302 clinical medicine Antigen Antigens CD Virology medicine Humans Lectins C-Type Receptor Mannan-binding lectin Mucous Membrane biology Epidermis (botany) Transmission (medicine) virus diseases Mucous membrane Lectin 030104 developmental biology Infectious Diseases medicine.anatomical_structure Mannose-Binding Lectins Langerhans Cells Immunology biology.protein HIV-1 030215 immunology |
| Zdroj: | Trends in microbiology. 25(3) |
| ISSN: | 1878-4380 |
| Popis: | Langerhans cells are specialized sentinels present in the epidermis expressing Langerin, a specific C-type lectin receptor involved in HIV capture and destruction. Recently, the specific mechanism leading to this HIV restriction was discovered. Nevertheless, Langerhans cells can be infected and the way HIV escapes this restriction needs to be unraveled. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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