Is the Severity of the Clinical Expression of Anorexia Nervosa Influenced by an Anxiety, Depressive, or Obsessive-Compulsive Comorbidity Over a Lifetime?
| Autor: | Elise Riquin, Agathe Raynal, Lama Mattar, Christophe Lalanne, France Hirot, Caroline Huas, Jeanne Duclos, EVHAN group, Sylvie Berthoz, Nathalie Godart, Hélène Roux, Marie Raphaële Thiébaud, Sarah Vibert, Tamara Hubert, Annaig Courty, Damien Ringuenet, Jean-pierre Benoit, Corinne Blanchet, Marie Rose Moro, Laura Bignami, Clémentine Nordon, Frédéric Rouillon, Solange Cook, Catherine Doyen, Marie-Christine Mouren Siméoni, Priscille Gerardin, Sylvie Lebecq, Marc-Antoine Podlipski, Claire Gayet, Malaika Lasfar, Marc Delorme, Xavier Pommereau, Stéphanie Bioulac, Manuel Bouvard, Jennifer Carrere, Karine Doncieux, Sophie Faucher, Catherine Fayollet, Amélie Prexl, Stéphane Billard, François Lang, Virginie Mourier-Soleillant, Régine Greiner, Aurélia Gay, Guy Carrot, Sylvain Lambert, Morgane Rousselet, Ludovic Placé, Jean-luc Venisse, Marie Bronnec, Bruno Falissard, Christophe Genolini, Christine Hassler, Jean-Marc Tréluyer, Olivier Chacornac, Maryline Delattre, Nellie Moulopo, Christelle Turuban, Auger Christelle |
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| Přispěvatelé: | Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Laboratoire de Psychologie des Pays de la Loire (LPPL), Université d'Angers (UA)-Université de Nantes - UFR Lettres et Langages (UFRLL), Université de Nantes (UN)-Université de Nantes (UN), CHU Rouen, Normandie Université (NU), School of Arts and Sciences [Lebanese American University] (SAS/LAU), Lebanese American University (LAU), Université Paris Diderot, Sorbonne Paris Cité, Paris, France, Université Paris Diderot - Paris 7 (UPD7), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Institut Mutualiste de Montsouris (IMM), Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 (SCALab), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Hôpital Saint-Vincent de Paul, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Agence Nationale de la Recherche, ANR Institut National de la Santé et de la Recherche Médicale, Inserm Fondation de France Ministère des Affaires Sociales et de la Santé, EVHAN study was supported by grants from the French Ministry of Health (PHRCN 2007, 2011 AOM11197, ANR Jeune chercheur, Bourse de thèse Eiffel) and from CNAM-TS, Fondation de France, Fondation MGEN, EHESP, AP-HP, CIFRE, and Contrats d’interface INSERM., Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193 (SCALab), HAL UVSQ, Équipe |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Generalized anxiety disorder [SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health RC435-571 body mass index macromolecular substances behavioral disciplines and activities anorexia nervosa 03 medical and health sciences 0302 clinical medicine Quality of life mental disorders medicine Psychiatry Depression (differential diagnoses) Original Research 2. Zero hunger business.industry medicine.disease anxiety Comorbidity 3. Good health 030227 psychiatry nutritional status Psychiatry and Mental health nervous system Anorexia nervosa (differential diagnoses) [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health depression Major depressive disorder Anxiety Erratum medicine.symptom business Body mass index 030217 neurology & neurosurgery |
| Zdroj: | Frontiers in Psychiatry, Vol 12 (2021) Frontiers in Psychiatry Frontiers in Psychiatry, 2021, 12, ⟨10.3389/fpsyt.2021.658416⟩ Frontiers in Psychiatry, Frontiers, 2021, 12, ⟨10.3389/fpsyt.2021.658416⟩ |
| ISSN: | 1664-0640 |
| Popis: | Purpose: The relationship between anxiety or depressive comorbidities, their chronology of onset, and the severity of anorexia nervosa (AN) is not well-studied. We hypothesize that the existence of a comorbidity, particularly before the onset of AN, is associated with greater severity of AN.Methods: One hundred seventy-seven subjects were assessed. The prevalence of major depressive disorder (MDD), obsessive-compulsive disorder (OCD), generalized anxiety disorder (GAD), and social phobia (SP) as well as their chronology of onset were studied. The assessment criteria of AN severity were the overall clinical condition, body mass index (BMI) on admission, lowest BMI, intensity of the eating symptoms, age at the onset of AN, illness duration, number of hospitalizations, and quality of life.Results: Patients with AN had the greatest clinical severity when they had a comorbid disorder over their lifetime, such as MDD, GAD, or SP. These comorbidities along with OCD were associated with a higher level of eating symptoms and a more altered quality of life. A profile of maximum severity was associated with a higher prevalence of MDD and GAD. Concerning the chronology of onset, the age at the start of AN was later in cases of MDD or GAD prior to AN.Conclusion: There seems to be an association between severity of AN and both MDD and GAD. The chronology of onset of the comorbidity did not seem to be associated with the severity. |
| Databáze: | OpenAIRE |
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