The Association Between Detectable Plasmatic Human Immunodeficiency Virus (HIV) Viral Load and Different Subgingival Microorganisms in Brazilian Adults With HIV: A Multilevel Analysis
| Autor: | Sandra Torres, Priscila Pavan, Viviane Tiago Pereira, Renata Souto, Ana Paula Vieira Colombo, Milton de Uzeda, Carmelo Sansone, Mario Vianna Vettore, Rodrigo Carvalho de Souza, Lucio Souza Gonçalves |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Dental Plaque Gingiva Eikenella corrodens HIV Infections Microbiology Veillonella Young Adult Prevotella nigrescens Candida albicans medicine Actinomyces Bacteroides Humans Tannerella forsythia Actinomyces gerencseriae Viremia Periodontal Diseases Aged Bacteria biology Dialister pneumosintes HIV Campylobacter Middle Aged Viral Load medicine.disease biology.organism_classification Capnocytophaga gingivalis Chronic periodontitis Bacterial Load stomatognathic diseases Biofilms Immunology Actinomyces naeslundii Periodontics Female Capnocytophaga Porphyromonas gingivalis Treponema denticola Brazil |
| Zdroj: | Journal of Periodontology. 85:697-705 |
| ISSN: | 1943-3670 0022-3492 |
| DOI: | 10.1902/jop.2013.130273 |
| Popis: | Background: This study investigates the association between detectable plasmatic human immunodeficiency virus (HIV) viral load (HVL) and high levels of periodontal- and non-periodontal-related microorganisms in the subgingival microbiota of individuals with HIV. Methods: Thirty-seven individuals with HIV were divided into two groups: 1) detectable HVL (n = 15); and 2) undetectable HVL (n = 22). Subgingival biofilm samples were obtained, and the levels of 35 microbial species were determined by the checkerboard DNA–DNA hybridization method. Periodontal clinical measures and laboratory and sociodemographic data were also registered. x2 test, Fisher exact test, and Mann-Whitney U test were used to compare groups. Multilevel ordinal regression models were used to test the association between HVL and the levels of 35 microbial species in subgingival biofilm, adjusted for confounders. Results: Of the 35 species studied, 11 (31.4%) showed higher mean levels in the detectable HVL group than undetectable HVL group (P |
| Databáze: | OpenAIRE |
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