Cutaneous sarcoids in captive African lions associated with feline sarcoid-associated papillomavirus infection
| Autor: | G. M. B. Orbell, S. Young, John S. Munday |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Lions
Male Feline sarcoid-associated papillomavirus Pathology medicine.medical_specialty Skin Neoplasms Mucocutaneous zone Polymerase Chain Reaction Virus law.invention Viral genetics law biology.animal medicine Animals Papillomaviridae Polymerase chain reaction CATS Paraffin Embedding General Veterinary biology Papilloma Papillomavirus Infections Sequence Analysis DNA Virology DNA Viral Animals Zoo Cattle Panthera Skin lesion |
| Zdroj: | Veterinary pathology. 48(6) |
| ISSN: | 1544-2217 |
| Popis: | Solitary and multiple cutaneous and mucocutaneous masses were identified in 5 of 24 captive African lions ( Panthera leo) over a 6-month-period. All masses were surgically excised, and all were histologically similar to equine and feline sarcoids. DNA was extracted from formalin-fixed, paraffin-embedded tissue. Polymerase chain reaction amplified DNA sequences that had been previously detected in feline sarcoids and clinically normal bovine skin. All lions had been fed a diet that included bovine carcasses that had not been skinned. Since the cessation of feeding bovine carcasses with cutaneous lesions, no additional skin lesions have been observed within any of the lions. Herein is described the clinical, gross, and histopathological findings of sarcoids in 5 captive lions. As the causative papillomavirus most likely has a bovine definitive host, it is hypothesized that the lions were exposed to the virus by feeding on bovine carcasses with skin still attached. |
| Databáze: | OpenAIRE |
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