A treatment planning comparison of contemporary photon-based radiation techniques for breast cancer
Autor: | Raphaël Moeckli, Wendy Jeanneret-Sozzi, Kristoffer Petersson, Michele Zeverino, François Bochud, Jean Bourhis, Archonteia Kyroudi |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty medicine.medical_treatment lcsh:R895-920 Multi-objective optimization lcsh:RC254-282 Tomotherapy 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Breast cancer Whole Breast Irradiation Planning comparison Medicine Radiology Nuclear Medicine and imaging Original Research Article Radiation treatment planning Dose sparing Radiation business.industry Standard treatment Pareto principle medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Pareto front 030220 oncology & carcinogenesis Radiology business Treatment planning Whole-breast irradiation |
Zdroj: | Physics and Imaging in Radiation Oncology, Vol 7, Iss, Pp 32-38 (2018) Physics and Imaging in Radiation Oncology, vol. 7, pp. 32-38 Physics and Imaging in Radiation Oncology |
ISSN: | 2405-6316 |
Popis: | Background and purpose: Adjuvant radiation therapy (RT) of the whole breast (WB) is still the standard treatment for early breast cancer. A variety of radiation techniques is currently available according to different delivery strategies. This study aims to provide a comparison of six treatment planning strategies commonly adopted for breast-conserving adjuvant RT and to use the Pareto concept in an attempt to assess the degree of plan optimization. Materials and methods: Two groups of six left- and five right-sided cases with different dose prescriptions were involved (22 patients in total). Field-in-Field (FiF), two and four Fields static-IMRT (sIMRT-2f and sIMRT-4f), Volumetric-Modulated-Arc-Therapy (VMAT), Helical Tomotherapy (HT) and Static-Angles Tomotherapy (TomoDirect™ – TD) were planned. Dose volume constraints were taken from the RTOG protocol 1005. Pareto fronts were built for a selected case to evaluate the reliability of the plan optimization process. Results: The best target dose coverage was observed for TD able to improve significantly (p |
Databáze: | OpenAIRE |
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