ParaStamp and Its Applications to Cell Patterning, Drug Synergy Screening, and Rewritable Devices for Droplet Storage
| Autor: | Jong Yueh Wang, Andrew M. Wo, Benjamin P C Chen, Ching-Te Kuo, Hsinyu Lee |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Materials science Polydimethylsiloxane Biomedical Engineering Nanotechnology 02 engineering and technology 021001 nanoscience & nanotechnology Cell patterning Article General Biochemistry Genetics and Molecular Biology Biomaterials 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology chemistry Drug development Hydrophobic surfaces 0210 nano-technology |
| Zdroj: | Advanced Biosystems. 1:1700048 |
| ISSN: | 2366-7478 |
| DOI: | 10.1002/adbi.201700048 |
| Popis: | Engineered materials have been employed as versatile tools to explore fundamental processes in cell biology/drug development as well as an approach towards intelligent devices, thereby becoming key components in modern technology. Herein, a ParaStamp technique is revealed to possess applications for cell patterning, drug screening, and rewritable functional patterning. The ParaStamp includes a micropatterned polydimethylsiloxane master and a liquid-phased paraffin oil generated at high temperature, which can transfer the patterned paramembrane onto varied material surfaces such as glass, polystyrene, and flexible foil. This technique is simple and cost-effective to meet the high-throughput requirement for industries. Taken together, the findings herein should provide general insights in cell biology, biodetection, and the development of smart hydrophobic surfaces. |
| Databáze: | OpenAIRE |
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