Loss to follow-up among patients receiving anti-tuberculosis treatment, Haiti, 2011-2015
| Autor: | J. P. Cegielski, Macarthur Charles, W. Morose, E. R. Schnaubelt, M. Richard, David L. Fitter |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty Tuberculosis business.industry Health Policy 030106 microbiology Hazard ratio Public Health Environmental and Occupational Health Human immunodeficiency virus (HIV) Psychological intervention virus diseases Original Articles Logistic regression medicine.disease_cause medicine.disease 03 medical and health sciences 0302 clinical medicine Anti tuberculosis Median time medicine 030212 general & internal medicine business Survival analysis |
| Zdroj: | Public health action. 8(4) |
| ISSN: | 2220-8372 |
| Popis: | Setting: Tuberculosis (TB) treatment facilities in Haiti. Objective: To assess factors associated with loss to follow-up (LTFU) among patients receiving treatment for tuberculosis (TB) in Haiti. Design: We analyzed Haiti's national surveillance data for patients started on anti-tuberculosis treatment from 2011 to 2015 to determine factors associated with LTFU using multivariable logistic regression and describe LTFU in terms of subnational units to target future intervention strategies. We also conducted a survival analysis to estimate hazard ratios of factors associated with time to LTFU. Results: Of 81 490 TB cases reported, 7423 (9.1%) were LTFU during anti-tuberculosis treatment, increasing from 7.1% in 2011 to 10.3% in 2015. Six high-volume facilities had significantly higher rates of LTFU (14.3-31.9%) than the rest of the country, accounting for 18.8% of all TB cases reported, but 41.7% of all LTFU patients. Male sex, previous treatment history, and human immunodeficiency virus infection were associated with higher rates of LTFU. The median time to LTFU was 94 days. Conclusion: A small number of facilities accounted for disproportionately high rates of LTFU. These results identify characteristics of facilities and individuals leading to concentrated interventions to reduce LTFU and improve treatment success. |
| Databáze: | OpenAIRE |
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