Plasminogen activator inhibitor 2: regulation of gene transcription during phorbol ester-mediated differentiation of U-937 human histiocytic lymphoma cells

Autor:	C. Hession, R. Rothenbühler, W.-D. Schleuning, Egbert K. O. Kruithof, A. Shaw, Robert L. Medcalf
Rok vydání:	1987
Předmět:	Transcription Genetic Cellular differentiation Molecular Sequence Data DNA Recombinant Biology chemistry.chemical_compound Transformation Genetic Transcription (biology) Complementary DNA Plasminogen Inactivators Escherichia coli Tumor Cells Cultured Humans RNA Messenger Molecular Biology Glycoproteins Base Sequence Cell Differentiation DNA Templates Genetic Cell Biology Molecular biology chemistry Tetradecanoylphorbol Acetate Plasminogen activator inhibitor-2 Phorbol Lymphoma Large B-Cell Diffuse Plasminogen activator Research Article Plasmids
Zdroj:	Molecular and Cellular Biology. 7:4564-4567
ISSN:	1098-5549 0270-7306
DOI:	10.1128/mcb.7.12.4564
Popis:	We have isolated and sequenced two cDNA clones coding for plasminogen activator inhibitor 2 (PAI-2). The cDNA was used to study the regulation of PAI-2 gene transcription by the tumor-promoting phorbol ester phorbol 12-myristate 13-acetate in the human histiocytic lymphoma cell line U-937. The tumor promoter caused a transient, 50-fold increase of PAI-2 gene transcription.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5c7c4c50764897bab5ff2cb2a75318 https://doi.org/10.1128/mcb.7.12.4564 Zobrazit plný text záznamu