Novel Insights into Pediatric Acute Lymphoblastic Leukemia Ophthalmic Relapses from a Nationwide Cohort Study
| Autor: | Solenne Le Louet, Véronique Icart, Marion Strullu, Arnaud Petit, Claire Freycon, Pascale Blouin, Jill Serre, Nicolas Rama, Yves Reguerre, Christophe Piguet, Marlène Pasquet, Audrey David, Pauline Simon, Marilyne Poiree, Liana Carausu, Fanny Rialland, Wadih Abouchahla, Paul Saultier, Stéphane Ducassou, Julie Valduga, André Baruchel, Yves Bertrand, Carine Domenech |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Cancer. 13:1272-1281 |
| ISSN: | 1837-9664 |
| DOI: | 10.7150/jca.64996 |
| Popis: | Ten to fifteen percent of children with acute lymphoblastic leukemia (ALL) relapse following treatment. Of these, less than 2% display ophthalmic relapses, which owing to their scarcity, are largely undocumented, leaving clinicians with few diagnostic and therapeutic recommendations, despite serious functional sequelae. We conducted a French multicenter retrospective study to collect all clinical, radiological, biological, and therapeutic data, and outcomes for children with ALL ophthalmic relapses. From 2000 to 2020, 20 ophthalmic relapses occurring after first-line therapy performed before January 1 |
| Databáze: | OpenAIRE |
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