Centenarians Differ in Their Comorbidity Trends During The 6 Years Before Death Compared to Individuals Who Died in Their 80s or 90s
| Autor: | Dagmar Dräger, Adelheid Kuhlmey, Christine Zwillich, Petra von Berenberg, Paul Gellert, Maria Klemt, Stefan Hörter, Monika Oedekoven |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Aging Younger age Longevity Comorbidity Cohort Studies Multiple Chronic Illnesses 03 medical and health sciences 0302 clinical medicine Germany Prevalence Health insurance medicine Humans 030212 general & internal medicine Aged 80 and over business.industry Confounding Age Factors medicine.disease Chronic Disease Lower prevalence Compression of morbidity Female Geriatrics and Gerontology business 030217 neurology & neurosurgery Cohort study Demography |
| Zdroj: | The Journals of Gerontology: Series A. 73:1357-1362 |
| ISSN: | 1758-535X 1079-5006 |
| DOI: | 10.1093/gerona/glx136 |
| Popis: | Background While compression of morbidity has now been studied in multiple cohorts, we hypothesize that centenarians might also have fewer chronic conditions as well. We assume that individuals who die as centenarians have less comorbidities and have a less steep rise of the number of comorbidities over the final years before death compared to those who died as nonagenarians (90-99 years) or octogenarians (80-89 years of age). Methods This German cohort study used health insurance data. The data contain complete information on diagnoses and health care transactions for the 6 years prior to death. The sample (N = 1,398; 34,735-person calendar quarters) is comprised of three groups of individuals; those who died as centenarians were compared with random samples of individuals who died as nonagenarians or as octogenarians. Community-dwelling and institutionalized individuals were included. Results One quarter prior to death, individuals who died as centenarians had, on average, 3.3 comorbidities. Octogenarians had 4.6 comorbidities one quarter prior to death. Further, there was a significant time-to-death by age-at-death interaction (B = -.03, p < .001), where centenarians showed a less steep increase in the number of comorbidities than the comparison groups in their last 6 years prior to death. Conclusions The lower prevalence of comorbidities in individuals who died as centenarians compared with those who died at a younger age reinforces the notion of centenarians as a selective group. Avoiding the confounding and potentially synergistic effects of having multiple chronic illnesses is likely vital to being able to survive to extreme ages. |
| Databáze: | OpenAIRE |
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