Coexistent Squamous Cell Carcinoma and Granular Cell Tumor of Head and Neck Region: Report of Two Very Rare Cases and Review of the Literature
| Autor: | Gennaro Ilardi, Luigi Califano, Gianfranco De Dominicis, Francesca Pagliuca, Massimo Mascolo, Giuseppe Ciancia, Grazia Salerno, Danila Caroppo, Francesco Merolla, Daniela Russo, Massimo Mesolella |
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| Přispěvatelé: | Caroppo, Danila, Salerno, Grazia, Merolla, Francesco, Mesolella, Massimo, Ilardi, Gennaro, Pagliuca, Francesca, De Dominicis, Gianfranco, Califano, Luigi, Ciancia, Giuseppe, Russo, Daniela, Mascolo, Massimo |
| Rok vydání: | 2017 |
| Předmět: |
Oncology
Larynx squamous cell carcinoma Adult Male medicine.medical_specialty Pathology Pseudoepitheliomatous Hyperplasia Pathology and Forensic Medicine Neoplasms Multiple Primary 03 medical and health sciences 0302 clinical medicine Tongue Internal medicine medicine Humans Basal cell granular cell tumor head and neck region Esophagus 030223 otorhinolaryngology Neuroectodermal tumor Head and neck Granular cell tumor business.industry Middle Aged medicine.disease stomatognathic diseases medicine.anatomical_structure Granular Cell Tumor Head and Neck Neoplasms 030220 oncology & carcinogenesis Carcinoma Squamous Cell Surgery Female Anatomy business |
| Zdroj: | International journal of surgical pathology. 26(1) |
| ISSN: | 1940-2465 |
| Popis: | Granular cell tumor (GCT), a relatively rare neuroectodermal tumor occurring most often in the head and neck region, is not uncommonly associated with pseudoepitheliomatous hyperplasia of the overlying surface epithelium, which may be at times nonreadily distinguishable from well-differentiated squamous cell carcinoma (SCC). To the best of our knowledge, only a handful of coexisting SCC and GCT, mostly described in the esophagus, have been reported in (the current) literature so far. We herein report 2 new cases of coexisting GCT and SCC of the head and neck region, located, respectively, in larynx and tongue; comment on their clinical, imaging, and pathologic features; and discuss their management. In the present work, we also review the literature concerning this association to contribute to the head and neck pathologists’ and surgeons’ awareness regarding the possibility of this association for an adequate surgical excision and a better management of these patients. |
| Databáze: | OpenAIRE |
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