Opana ER abuse and thrombotic thrombocytopenic purpura (TTP)-like illness: a rising risk factor in illicit drug users
| Autor: | Lovely Chhabra, Vinod K. Chaubey, Aaysha Kapila, Jeffery Summers |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Drug
medicine.medical_specialty Thrombotic microangiopathy media_common.quotation_subject Thrombotic thrombocytopenic purpura Article Young Adult medicine Humans Young adult Substance Abuse Intravenous Intensive care medicine media_common Oxymorphone Purpura Thrombotic Thrombocytopenic Thrombotic Microangiopathies business.industry Opioid-Related Disorders General Medicine medicine.disease Analgesics Opioid Polysubstance dependence Anesthesia Cellulitis Female business medicine.drug |
| Zdroj: | Case Reports. 2014:bcr2013203122-bcr2013203122 |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2013-203122 |
| Popis: | We report the case of a 22 year-old-woman who presented with upper extremity cellulitis secondary to an infiltration of illicit intravenous drug use. She confessed to the intravenous use of Opana ER (an extended release oral formulation of oxymorphone) which is an opioid drug approved only for oral use. She was found to have clinical evidence of profound thrombotic microangiopathy which resulted due to the intravenous use of Opana ER. She showed full clinical improvement after withholding drug and supportive clinical care. Recent report of Opana ER intravenous abuse was published from Tennessee county and has now been increasingly recognised as one of the causes of thrombocytopenia which mimicks clinically as thrombotic thrombocytopenic purpura. Physicians should be aware of this association as the lack of familiarity to this can pose serious management dilemmas for our patients (especially the polysubstance abusers). |
| Databáze: | OpenAIRE |
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