Rotavirus serology and excretion in hospitalized non-diarrhoeal patients
| Autor: | A. Moosa, I. E. Haffejee |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Diarrhea
Male Rotavirus medicine.medical_specialty 030231 tropical medicine Reoviridae Antibodies Viral medicine.disease_cause Gastroenterology Asymptomatic Rotavirus Infections Serology Feces South Africa 03 medical and health sciences fluids and secretions 0302 clinical medicine 030225 pediatrics Internal medicine medicine Humans Prospective Studies Child Prospective cohort study Antigens Viral biology business.industry Infant Newborn Infant biology.organism_classification Child Preschool Pediatrics Perinatology and Child Health Immunology Etiology Female medicine.symptom business |
| Zdroj: | Annals of Tropical Paediatrics. 10:173-178 |
| ISSN: | 1465-3281 0272-4936 |
| DOI: | 10.1080/02724936.1990.11747426 |
| Popis: | Despite the well-recognized association between rotavirus (RV) and infantile diarrhoeal disease, a few studies have shown that the isolation rate of RV from the faeces of non-diarrhoeal patients can be high, suggesting that the finding of RV in the stools of individual gastro-enteritis (GE) patients need not necessarily denote an aetiological relationship. A prospective study of rotavirus serology and stool excretion was carried out in a group of non-diarrhoeal paediatric patients. A positive ELISA for RV antigen was found in 13.3% children, which compared favourably with an asymptomatic RV-excretion rate of 16.2% found in normal subjects in the community, but differed significantly from the 54.6% RV-excretion rate found in hospitalized GE patients. This confirms that RV is an important enteropathogen. Furthermore, approximately half of the non-diarrhoeal infants acquired nosocomial RV infections in hospital, most of these being asymptomatic. One-sixth of asymptomatic RV excretors showed evidence of prior exposure to rotavirus. |
| Databáze: | OpenAIRE |
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