Risk factors for pancreatic cancer in orientals
| Autor: | Full-Young Chang, Chi-Te Lee, Shou-Dong Lee |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Pancreatic disease Taiwan Mongoloid Diabetes Complications Risk Factors Diabetes mellitus Internal medicine Pancreatic cancer medicine Diabetes Mellitus Humans Risk factor Aged Retrospective Studies Hepatology business.industry Smoking Gastroenterology Retrospective cohort study Odds ratio Middle Aged medicine.disease Surgery Pancreatic Neoplasms medicine.anatomical_structure Female Pancreas business |
| Zdroj: | Journal of gastroenterology and hepatology. 11(5) |
| ISSN: | 0815-9319 |
| Popis: | In order to assess what the risk factors for patients with pancreatic cancer (PC) in Taiwan are, a retrospective study was undertaken among 282 consecutively enrolled inpatients with confirmed pancreatic cancer within the past 5 years. For comparison, 282 age- and sex-matched controls were consecutively enrolled. A history of smoking, consumption of alcohol, diabetes mellitus, cholecystectomy and gastric surgery were thoroughly reviewed. Smoking and diabetes mellitus were very common among patients with pancreatic cancer compared with controls (P < 0.01). A significant linear trend towards an increased odds ratios (OR) for the development of PC with a higher level of smoking was seen (P < 0.001). Diabetes mellitus (DM) also exhibited an increased risk (OR: 2.84; P < 0.01), while the risk still existed among those patients who had a diabetic history of more than 3 years. Among 129 histologically established PC patients, smoking remained as a risk factor for PC, while the linear trend with an increasing OR with increasing levels of smoking was confirmed again (P < 0.01). DM, particularly over the long-term, was also a risk factor for those histologically established PC patients. In summary, cigarette smoking and existing diabetes mellitus are probable risk factors for the development of pancreatic cancer in Taiwan. |
| Databáze: | OpenAIRE |
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