Effects of Fetal Number and Multifetal Reduction on Length of In Vitro Fertilization Pregnancies
Autor: | David B. Seifer, Gary N. Frishman, Ray V. Haning, Carol Wheeler, Deborah J. Pierce, Helayne M. Silver |
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Rok vydání: | 1996 |
Předmět: |
medicine.medical_specialty
Time Factors medicine.medical_treatment Gestational Age Fertilization in Vitro Pregnancy Humans Medicine Fetal Death Gynecology Fetus In vitro fertilisation Fetal death business.industry Obstetrics Incidence (epidemiology) Infant Newborn Obstetrics and Gynecology Gestational age medicine.disease Pregnancy Reduction Multifetal Regression Analysis Gestation Female Pregnancy Multiple business |
Zdroj: | Obstetrics & Gynecology. 87:964-968 |
ISSN: | 0029-7844 |
DOI: | 10.1016/0029-7844(96)00059-2 |
Popis: | To determine the effects of multifetal reduction and other variables on the duration of gestation of in vitro fertilization (IVF) pregnancies.All 274 IVF pregnancies from the inception of the Women and Infants' Hospital IVF Program on May 26, 1988, until December 31, 1993, were evaluated.Spontaneous reduction occurred in ten pregnancies, and multifetal reduction was elected in 28 multiple gestations. Among 260 pregnancies that remained viable beyond 20 weeks, 162 singletons (37.9 +/- 0.29 weeks; mean +/- standard error) had a longer mean gestation than did 64 twins (34.6 +/- 0.61 weeks), 25 pregnancies reduced to twins (33.4 +/- 1.0 weeks), or nine triplets (29.7 +/- 1.9 weeks). Triplets delivered 4.9 weeks earlier than nonreduced twins (P.05) and 3.7 weeks before twins resulting from multifetal pregnancy reduction (P.05). Regression analysis showed that at the 8-week ultrasound, each viable fetus could be expected to reduce the duration of the gestation by about 3.6 weeks, and each fetus reduced medically or as a result of natural causes could be expected to prolong the gestation by approximately 3.0 weeks. Only 14% of triplet pregnancies underwent spontaneous multifetal reduction.Multifetal reduction of pregnancies with three or more fetuses was beneficial and increased the duration of gestation. |
Databáze: | OpenAIRE |
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