A systematic review of the clinical and radiographic features of hybrid central giant cell granuloma lesions of the jaws
| Autor: | Rasha S Alrasheed, Rand F Alsaif, Noura A. Alsufyani, Reem M Aldosary |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent Biopsy Radiography Odontogenic Tumors Mandible Young Adult 03 medical and health sciences 0302 clinical medicine Granuloma Giant Cell Humans Medicine Child General Dentistry business.industry food and beverages 030206 dentistry General Medicine Middle Aged medicine.disease stomatognathic diseases surgical procedures operative Fibroma Ossifying Female business 030217 neurology & neurosurgery Central giant-cell granuloma |
| Zdroj: | Acta Odontologica Scandinavica. 79:124-131 |
| ISSN: | 1502-3850 0001-6357 |
| DOI: | 10.1080/00016357.2020.1797160 |
| Popis: | Central giant cell granuloma (CGCG) can coexist with other benign lesions of the jaw. These hybrid lesions are diagnostically challenging to both oral pathologists and radiologists. This work systematically reviews the clinical and radiographic features of hybrid-CGCG lesions in the jaws.Three reviewers conducted an electronic search of five databases for histologically diagnosed hybrid-CGCG lesions in human jaws.Thirty-four of 1224 articles met the inclusion criteria. Of 39 hybrid-CGCG lesions, 14 (35.9%) were central odontogenic fibroma, 11 (28.2%) were central ossifying fibroma, seven (17.9%) were fibrous dysplasia, and seven (17.9%) were other bone conditions. There were 22 females and 17 males with a mean age of 30.5 ± 19.9 years. 89.5% of hybrid-CGCG lesions were well defined, 57.9% were non-corticated, 60.5% were radiolucent, and 66.7% were in the posterior mandible. Most hybrid lesions affected the cortical plates by thinning, expansion, or perforation (93.1%), displaced, or resorbed teeth (60%).The radiographic features of hybrid-CGCG lesions vary according to the concurrent bony lesion. Hybrid-CGCG lesions altered the radiographic appearance with the following entities: fibrous dysplasia, melorheostosis, and Paget's disease. Optimal imaging modalities are crucial to detail radiographic features and direct representative biopsy of suspicious sites that may host a CGCG hybridisation. |
| Databáze: | OpenAIRE |
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