Lignocaine gel used for lubrication of intranasal and endotracheal tubes in premature neonates
| Autor: | Flachs H, Hjelt K, Halvorsen Ac, Bendixen D |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty Lidocaine medicine.medical_treatment Infant Premature Diseases Absorption (skin) Positive-Pressure Respiration Intensive care Lubrication Blood plasma Intubation Intratracheal medicine Humans Intubation Prospective Studies Continuous positive airway pressure business.industry Infant Newborn Gestational age General Medicine Surgery Anesthesia Pediatrics Perinatology and Child Health Female Nasal administration business Gels Infant Premature medicine.drug |
| Zdroj: | Acta Paediatrica. 83:493-497 |
| ISSN: | 1651-2227 0803-5253 |
| DOI: | 10.1111/j.1651-2227.1994.tb13065.x |
| Popis: | Bendixen D, Halvorsen A-C, Hjelt K, Flachs H. Lignocaine gel used for lubrication of intranasal and endotracheal tubes in premature neonates. Acta Prediatr 1994;83:493–7. Stockholm. ISSN 0803–5253 In this study, we have measured the plasma concentration of lignocaine and its metabolite, monoethylglycinxylidin, in 19 premature neonates (gestational age 33 weeks) when lignocaine gel was used for lubrication of an intranasal tube (during continuous positive airway pressure treatment) or an endotracheal tube (for intubation). We did not find any correlation between plasma concentration of lignocaine or monoethylglycinxylidin and weight of the infant (range 795–2530 g). None of the neonates had toxic levels of lignocaine. One neonate had an exceptionally high but not toxic plasma level of monoethylglycinxylidin. However, this neonate had been treated for severe seizures with an iv infusion of lignocaine up to 13 h before the study. In conclusion, we found it safe to use moderate amounts of lignocaine (i.e. 0.3 ml/kg of lignocaine gel 20 mg/ml) for lubricating both intranasal and endotracheal tubes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text