Factors Associated With Increased Hospital Length of Stay in Peritoneal Dialysis Patients With Peritonitis: A Need for Antimicrobial Stewardship?
Autor: | Robert B. Canada, Danielle Padgett, Taylor Morrisette, Joanna Q. Hudson |
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Rok vydání: | 2018 |
Předmět: |
Pharmacology
Nephrology medicine.medical_specialty education.field_of_study business.industry medicine.medical_treatment Population Peritonitis Retrospective cohort study Original Articles Pharmacy medicine.disease Antimicrobial 030226 pharmacology & pharmacy Peritoneal dialysis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Antimicrobial stewardship Pharmacology (medical) 030212 general & internal medicine Complication education business |
Zdroj: | Hosp Pharm |
ISSN: | 1945-1253 0018-5787 |
DOI: | 10.1177/0018578718817944 |
Popis: | Background: Peritonitis remains a complication of peritoneal dialysis (PD) and contributes to morbidity. Adherence to evidence-based recommendations should resolve peritonitis within 5 days; however, hospital length of stay (LOS) for patients with PD-associated peritonitis (PDAP) varies. Factors contributing to increased LOS and vigilance with antimicrobial stewardship (ASP) in this population are not well described. Methods: This was a system-wide, retrospective cohort of adult patients presenting with PDAP from August 2012 to August 2017. Patients were divided into 2 groups based on LOS: 180 mg/dL ( P = .028). Opportunities for antimicrobial de-escalation were identified in 24 (52%) and 22 (50%) patients in the reduced and prolonged LOS groups, respectively; however, de-escalation occurred in only 5 (21%) and 6 (27%) of these patients. There were no differences in mortality or 30-day readmissions. Conclusions: Longer LOS was influenced by acuity of illness and possibly lack of enforced ASP. Improvement of ASP within the PDAP population is necessary. |
Databáze: | OpenAIRE |
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