Latent tuberculosis infection and tuberculosis in children and adolescents

Autor: Flavio Sarno, Cassia Satsuki Ishikawa, Olivia Mari Matsuo
Jazyk: angličtina
Předmět:
0301 basic medicine
Thorax
Male
Radiography
lcsh:Medicine
0302 clinical medicine
030212 general & internal medicine
Child
Child health
biology
Latent tuberculosis
General Medicine
Child
Preschool
Female
Radiography
Thoracic
Original Article
Serviços de saúde da criança
Brazil
medicine.medical_specialty
Tuberculosis
Tomography Scanners
X-Ray Computed
Adolescent
030106 microbiology
Criança
Statistics
Nonparametric
Mycobacterium tuberculosis
03 medical and health sciences
Age Distribution
Latent Tuberculosis
Internal medicine
medicine
Humans
Tuberculose
In patient
Sex Distribution
Tuberculin test
Tuberculosis
Pulmonary
Retrospective Studies
business.industry
Tuberculin Test
lcsh:R
Infant
Retrospective cohort study
medicine.disease
biology.organism_classification
Child health services
Saúde da criança
business
Zdroj: Einstein (São Paulo), Vol 16, Iss 3
Einstein
einstein (São Paulo) v.16 n.3 2018
Einstein (São Paulo)
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron:IIEPAE
ISSN: 2317-6385
Popis: Objective: To describe the characteristics of patients diagnosed with tuberculosis and latent tuberculosis infection. Methods: A retrospective study, between 2012 and 2015, with data from patients of Programa Einstein na Comunidade de Paraisópolis. To evaluate possible factors associated with patient's sex and diagnoses of tuberculosis and latent tuberculosis infection, χ2 or Fisher's exact tests were used for qualitative variables, and Mann-Whitney test for quantitative or ordinal qualitative variables. Results: A total of 77 patients were evaluated. Age ranged from 6 months to 13.4 years, with a majority of males (54.5%), aged zero to 4 years (54.5%), diagnosed with latent tuberculosis infection (64.9%), and classified as eutrophic (71.2%). The tuberculin test was positive in 92% and in most cases the values were above 10mm (68.0%). Approximately three-quarters of chest X-ray tests were normal (72.7%). After chest X-ray, computed tomography of thorax was the most ordered exam (29.9%), followed by smear and culture for Mycobacterium tuberculosis in the gastric aspirate (28.6%). The frequencies of altered chest X-ray (70.4% versus 4.0%), computed tomography of thorax requests (55.6% versus 16.0%) and other tests requested (81.5% versus 38.0%) were significantly higher in patients with a diagnosis of tuberculosis, relative to those with latent tuberculosis infection, respectively. Conclusion: In our sample, proportions of altered chest X-ray, and performing computed tomography of thorax and other tests in patients diagnosed with tuberculosis were higher than in those with latent tuberculosis infection.
Databáze: OpenAIRE
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