Opsoclonus-Myoclonus Syndrome, a Post-Infectious Neurologic Complication of COVID-19: Case Series and Review of Literature
| Autor: | Sharmin Aghavali, Maryam Zaribafian, Mansoureh Babadi, Maryam Pouranian, Peyman Daraie, Mehrnoush Mehrabani, Maziar Emamikhah, Mehdi Jalili, Mohammad Rohani, Fahimeh Mohaghegh |
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| Rok vydání: | 2020 |
| Předmět: |
Myoclonus
Male 0301 basic medicine myalgia Pediatrics Levetiracetam Neurology Review Azithromycin Viral infection Clonazepam 0302 clinical medicine Pandemic Opsoclonus myoclonus syndrome Neurological findings Middle Aged Anticonvulsants Female medicine.symptom Hydroxychloroquine medicine.drug Parainfectious Adult medicine.medical_specialty Ataxia Fever Coronavirus disease 2019 (COVID-19) Clinical Neurology 03 medical and health sciences Cellular and Molecular Neuroscience Oseltamivir Virology medicine Humans Opsoclonus-Myoclonus Syndrome SARS-CoV-2 business.industry Valproic Acid Neurologic complication other COVID-19 Opsoclonus Myalgia medicine.disease COVID-19 Drug Treatment Dyspnea 030104 developmental biology Cough Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Neurovirology Journal of NeuroVirology |
| DOI: | 10.20944/preprints202012.0466.v1 |
| Popis: | Opsoclonus-myoclonus-ataxia syndrome is a heterogeneous constellation of symptoms ranging from full combination of these three neurological findings to varying degree of isolated individual sign. Since the emergence of coronavirus disease 2019 (COVID-19), neurological symptoms, syndromes and complications associated with this multi-organ viral infection have been reported and the various aspects of neurological involvement are increasingly uncovered. As a neuro-inflammatory disorder in nature, one would expect to observe opsoclonus-myoclonus syndrome after a prevalent viral infection in a pandemic scale, as it has been the case for many other neuro-inflammatory syndromes. We report seven cases of opsoclonus-myoclonus syndrome presumably para-infectious in nature and discuss their phenomenology, their possible pathophysiological relationship to COVID-19 and diagnostic and treatment strategy in each case. Finally we review the relevant data in the literature regarding the opsoclonus-myoclonus syndrome and possible similar cases associated with COVID-19 and its diagnostic importance for clinicians in various fields of medicine encountering COVID-19 patients and its complications. |
| Databáze: | OpenAIRE |
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