Quality of life and health status before and after ileal pouch-anal anastomosis for ulcerative colitis

Autor: M.R. Goos, J.T. Heikens, Hein G. Gooszen, I.J.M. de Vries, H.J.M. Oostvogel, C.J.H.M. van Laarhoven
Přispěvatelé: Medical and Clinical Psychology
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: British Journal of Surgery, 99, 263-9
British Journal of Surgery, 99(2), 263-269. John Wiley and Sons Ltd
British Journal of Surgery, 99, 2, pp. 263-9
ISSN: 0007-1323
DOI: 10.1002/bjs.7711
Popis: Background Ileal pouch–anal anastomosis (IPAA) is considered the surgical treatment of choice for patients with ulcerative colitis. Quality of life (QoL) and health status are the most important patient-related outcomes. Studies investigating QoL are often cross-sectional and focus on health status. This longitudinal study evaluated QoL and health status after IPAA for ulcerative colitis and compared these with reference data from a healthy population. Methods Patients with ulcerative colitis who underwent a pouch operation between 2003 and 2008 completed validated questionnaires for QoL and health status. Questionnaires were completed before pouch surgery, and 6, 12, 24 and 36 months after operation. The effect of IPAA on QoL and health status was analysed, and data were compared with reference values from the healthy Dutch population. Results Data were obtained for 30 of the 32 patients. Six months after IPAA, QoL was at least comparable with that of the reference population in four of six domains. Twelve months after IPAA, overall QoL had improved, supported by findings in three QoL domains. Six months after IPAA, health status was comparable to that of the reference population in three of eight dimensions, and after 3 years it was at least comparable in five dimensions. Conclusion QoL and health status increased after IPAA and reached levels comparable with those of the healthy reference population in a majority of domains and dimensions. QoL was restored first after IPAA, followed by health status.
Databáze: OpenAIRE