Naso-gastric or naso-jejunal decompression after partial distal gastrectomy for gastric cancer. Final results of a multicenter prospective randomized trial
| Autor: | Franco Roviello, Massimo Framarini, Paolo Morgagni, Giovanni Battista Doglietto, Fabio Pacelli, Marcello Covino, Riccardo Casadei, Fausto Rosa, Giovanni de Manzoni, Luigi Cristadoro, Corrado Pedrazzani, Annibale Donini, Daniele Marrelli, Luca Cozzaglio |
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| Přispěvatelé: | Pacelli F, Rosa F, Marrelli D, Morgagni P, Framarini M, Cristadoro L, Pedrazzani C, Casadei R, Cozzaglio L, Covino M, Donini A, Roviello F, de Manzoni G, Doglietto GB. |
| Rok vydání: | 2013 |
| Předmět: |
Decompression
Male Cancer Research medicine.medical_specialty Anastomosis Settore MED/18 - CHIRURGIA GENERALE medicine.medical_treatment Gastroenterology Roux-en-Y Postoperative Complications Stomach Neoplasms Surgical Internal medicine naso-jejunal medicine Humans Prospective Studies Elective surgery Prospective cohort study Aged Billroth II business.industry Medicine (all) Anastomosis Roux-en-Y General Medicine Middle Aged Decompression Surgical Gastroenterostomy gastrectomy Surgery Treatment Outcome Oncology Partial distal gastrectomy Female Gastrectomy Gastric cancer Gastric decompression business naso-gastric Gastric cancer Partial distal gastrectomy Gastric decompression Abdominal surgery |
| Zdroj: | Gastric Cancer. 17:725-732 |
| ISSN: | 1436-3305 1436-3291 |
| DOI: | 10.1007/s10120-013-0319-x |
| Popis: | BACKGROUND: Only a few, small, monocentric randomized controlled trials (RCTs) have compared routine vs. no placement of a nasogastric or nasojejunal tube decompression (NG/NJT) in patients undergoing partial distal gastrectomy (PDG) for gastric cancer. However, to our knowledge, no multicenter prospective RCT has analyzed the role of decompression after both the Billroth II (BII) procedure and Roux-en-Y (RY) gastrojejunostomy. The aim of this study was to determine whether NG/NJT prevents the consequences of postoperative ileus after PDG for gastric cancer after both BII reconstruction and RY. METHODS: Two hundred seventy patients undergoing PDG for gastric cancer were randomly assigned NG/NJT placement (NG/NJT group) or not (no-NG/NJT group) with either Billroth II gastrojejunostomy or Roux-en-Y gastrojejunostomy. The patients were monitored for postoperative complications, mortality, and postoperative course. RESULTS: By January 2010 to June 2012, among 270 patients undergoing PDG for gastric cancer, 134 were randomly assigned to NG/NJT placement (NG/NJT group) and 136 to no decompression (no-NG/NJT group). Time to passage of flatus was significantly shorter in the NG/NJT group than in the no-NG/NJT group, but only after RY reconstruction (3.3 ± 1.5 vs. 4.3 ± 1.6 days, P < 0.001, respectively). Postoperative abdominal distention was significantly lower in the NG/NJT group than in the no-NG/NJT group after both BII and the RY procedure (P < 0.001). No significant differences in postoperative mortality or morbidity, especially anastomotic leakage or intra-abdominal sepsis, were observed between the groups. CONCLUSION: Routine placement of an NG/NJT after BII and RY PDG is not necessary in elective surgery for gastric cancer. |
| Databáze: | OpenAIRE |
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